1989 Italian Open – Men's singles

Alberto Mancini won in the final 6–3, 4–6, 2–6, 7–6, 6–1 against Andre Agassi.

Ivan Lendl was the defending champion but did not compete this year.

Seeds

 * 1) 🇸🇪 Mats Wilander (third round)
 * 2) 🇺🇸 Andre Agassi (final)
 * 3) 🇸🇪 Kent Carlsson (first round)
 * 4)  Miloslav Mečíř (first round)
 * 5) 🇺🇸 Jimmy Connors (third round)
 * 6) 🇪🇸 Emilio Sánchez (third round)
 * 7) 🇺🇸 Aaron Krickstein (second round)
 * 8) 🇦🇷 Guillermo Pérez Roldán (quarterfinals)
 * 9)  Ronald Agénor (first round)
 * 10) 🇦🇺 Darren Cahill (third round)
 * 11) 🇦🇷 Alberto Mancini (champion)
 * 12) 🇪🇨 Andrés Gómez (first round)
 * 13) 🇵🇪 Jaime Yzaga (third round)
 * 14) 🇦🇹 Horst Skoff (first round)
 * 15)  Marcelo Filippini (second round)
 * 16) 🇦🇺 Mark Woodforde (first round)