1990–91 Purdue Boilermakers men's basketball team

The 1990–91 Purdue Boilermakers men's basketball team represented Purdue University during the 1990–91 college basketball season. Led by head coach Gene Keady, the Boilermakers earned the #7 seed in the Midwest Region of the NCAA tournament, but were defeated in the first round by Temple, finishing the season with a 17–12 record (9–9 Big Ten).

Schedule and results
!colspan=6 style=| Non-conference regular season

!colspan=6 style=| Big Ten Regular Season

!colspan=6 style=| NCAA Tournament

Team players drafted into the NBA
For the second consecutive year, a Purdue player was taken with the 39th overall pick.