1990–91 Xavier Musketeers men's basketball team

The 1990–91 Xavier Musketeers men's basketball team represented Xavier University from Cincinnati, Ohio in the 1990–91 season. Led by head coach Pete Gillen, the Musketeers finished with a 22–10 record (11–3 MCC), won the MCC regular season and conference tournament titles, and received an automatic bid to the NCAA tournament as the #14 seed in the Midwest region. In the NCAA tournament, the Musketeers defeated #3 seed Nebraska, then lost to #11 seed Connecticut in the second round.

Schedule and results
!colspan=9 style=| Regular season

!colspan=9 style=| Midwestern Collegiate Conference tournament

!colspan=9 style=| NCAA Tournament