1990 US Open – Women's singles

Gabriela Sabatini defeated the two-time defending champion Steffi Graf in the final, 6–2, 7–6(7–4) to win the women's singles tennis title at the 1990 US Open. It was her first and only major singles title, despite reaching eighteen semifinals and three finals during her career. The final was a rematch of the 1988 final and the 1989 semifinals. Sabatini became the first Argentine to win the title.

Seeds
The seeded players are listed below. Sabatini is the champion; others show the round in which they were eliminated.

• # Steffi Graf (final)

• # 🇺🇸 Martina Navratilova (fourth round)

• # Monica Seles (third round)

• # 🇺🇸 Zina Garrison (quarterfinals)

• # 🇦🇷 Gabriela Sabatini (champion)

• # 🇪🇸 Arantxa Sánchez Vicario (semifinals)

• # 🇧🇬 Katerina Maleeva (fourth round)

• # 🇺🇸 Mary Joe Fernández (semifinals)

• # Manuela Maleeva-Fragnière (quarterfinals)

• # 🇪🇸 Conchita Martínez (third round)

• # Helena Suková (fourth round)

• # Jana Novotná (quarterfinals)

• # 🇺🇸 Jennifer Capriati (fourth round)

• # Natasha Zvereva (second round)

• # 🇦🇹 Judith Wiesner (fourth round)

• # 🇦🇹 Barbara Paulus (fourth round)