1991–92 DePaul Blue Demons men's basketball team

The 1991–92 DePaul Blue Demons men's basketball team represented DePaul University as a member of the newly formed Great Midwest Conference during the 1991–92 NCAA Division I men's basketball season. They were led by head coach Joey Meyer, in his 8th season, and played their home games at the Rosemont Horizon in Rosemont.

Schedule and results
!colspan=9 style=| Regular season

!colspan=12 style=|Great Midwest tournament

!colspan=9 style=| NCAA Tournament

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