1991 Copa Interamericana

The 1991 Copa InterAmericana was the 14th. edition of the Copa Interamericana. The final was contested by Mexican Club Puebla (winner of 1991 CONCACAF Champions' Cup) and Chilean club Colo-Colo (champion of 1991 Copa Libertadores). The final was played under a two-leg format in September 1992.

The first leg was held in Estadio Olímpico in Villahermosa, where Colo-Colo easily beat Puebla 4–1. The second leg was played at Estadio Monumental David Arellano in Santiago, with another Colo-Colo win over Puebla (3–1). With two wins and a 7–2 aggregate score, the Chilean side won their first Interamericana trophy.