1991 Jacksonville State Gamecocks football team

The 1991 Jacksonville State Gamecocks football team represented Jacksonville State University as a member of the Gulf South Conference (GSC) during the 1991 NCAA Division II football season. Led by seventh-year head coach Bill Burgess, the Gamecocks compiled an overall record of 12–1 with a mark of 6–0 in conference play, winning the GSC title. For the fourth consecutive season, Jacksonville State advanced to the NCAA Division II Football Championship playoffs, beating in the first round,  in the quarterfinals, and   in the semifinals before losing to Pittsburg State in the championship game.