1991 Lipton International Players Championships – Women's singles

Defending champion Monica Seles defeated Gabriela Sabatini in the final, 6–3, 7–5 to win the women's singles tennis title at the 1991 Miami Open.

Seeds
All seeds received a bye into the second round.

🇩🇪 Steffi Graf (semifinals) Monica Seles (champion) 🇦🇷 Gabriela Sabatini (final) 🇺🇸 Mary Joe Fernández (semifinals) 🇺🇸 Zina Garrison-Jackson (quarterfinals) 🇺🇸 Jennifer Capriati (quarterfinals) Manuela Maleeva-Fragniere (quarterfinals) Natasha Zvereva (second round) 🇦🇹 Barbara Paulus (fourth round) 🇫🇷 Nathalie Tauziat (fourth round) 🇨🇦 Helen Kelesi (second round) 🇺🇸 Amy Frazier (third round) 🇵🇪 Laura Gildemeister (third round) Rosalyn Fairbank-Nideffer (second round) 🇯🇵 Naoko Sawamatsu (third round) 🇮🇹 Raffaella Reggi (fourth round) 🇺🇸 Lori McNeil (third round) Manon Bollegraf (second round) 🇸🇪 Catarina Lindqvist (second round) 🇺🇸 Susan Sloane (second round) 🇺🇸 Gretchen Magers (third round) Regina Rajchrtová (fourth round) 🇺🇸 Meredith McGrath (third round) 🇺🇸 Carrie Cunningham (second round) 🇦🇺 Julie Halard (second round) 🇺🇸 Ann Grossman (third round) 🇺🇸 Marianne Werdel (fourth round) Cathy Caverzasio (second round) 🇩🇪 Wiltrud Probst (second round) Eva Švíglerová (third round) 🇺🇸 Stephanie Rehe (second round) 🇦🇺 Elizabeth Smylie (third round)

Seeds
🇺🇸 Camille Benjamin (Promoted to Main Draw) 🇺🇸 Renata Baranski (second round) 🇦🇷 Bettina Fulco (second round) 🇫🇷 Nathalie Guerrée (first round) 🇬🇧 Clare Wood (qualified) 🇩🇪 Eva Pfaff (second round) 🇫🇷 Maïder Laval (qualifying competition) 🇦🇺 Michelle Jaggard (second round) 🇧🇪 Sandra Wasserman (qualified) 🇺🇸 Hu Na (first round) 🇧🇷 Cláudia Chabalgoity (second round) 🇳🇿 Claudine Toleafoa (qualified) 🇫🇷 Noëlle van Lottum (first round) 🇫🇷 Pascale Etchemendy (first round) 🇧🇷 Andrea Vieira (first round) 🇳🇿 Julie Richardson (qualifying competition)

Qualifiers
🇨🇦 Rene Simpson-Alter 🇺🇸 Stacey Schefflin 🇫🇷 Nathalie Housset 🇳🇿 Claudine Toleafoa 🇬🇧 Clare Wood 🇮🇱 Yael Segal Miriam Oremans 🇫🇮 Petra Thorén