1991 Mississippi Valley State Delta Devils football team

The 1991 Mississippi Valley State Delta Devils football team represented Mississippi Valley State University as a member of the Southwestern Athletic Conference (SWAC) during the 1991 NCAA Division I-AA football season. Led by second-year head coach Larry Dorsey, the Delta Devils compiled an overall record of 7–3–1, with a conference record of 3–3–1, and finished tied for fourth in the SWAC.