1999–2000 Botswana Premier League

The 1999–2000 Botswana Premier League, also known as the 1999–2000 Castle Super League for sponsorship reasons, was the 23rd season of the Botswana Premier League. It was played from 4 September 1999 to 17 May 2000.

Mogoditshane Fighters, who were the defending champions, would go on to successfully defend both the league title and the FA Cup. The season was also marked by the relegation of former champions Gaborone United.

Team changes
Due to the transitional nature of the 1999 season, there were no changes for the 1999–2000 season.