1999–2000 George Mason Patriots men's basketball team

The 1999–2000 George Mason Patriots Men's basketball team represents George Mason University during the 1999–2000 NCAA Division I men's basketball season. This was the 34th season for the program, the third under head coach Jim Larrañaga. The Patriots played their home games at the Patriot Center in Fairfax, Virginia.

Honors and awards
Colonial Athletic Association Player of the Year
 * George Evans

Colonial Athletic Association All-Conference Team
 * George Evans
 * Erik Herring (2nd team)

Colonial Athletic Association All-Defensive Team
 * George Evans

Colonial Athletic Association Dean Ehlers Award
 * Keith Holdan

Schedule and results
!colspan=12 style=| Non-conference regular season

!colspan=12 style=|CAA regular season

!colspan=12 style=|2000 CAA tournament