1999 Campionati Internazionali di Sicilia – Singles

Mariano Puerta was the defending champion, but lost in the second round to Albert Costa.

Arnaud Di Pasquale won the title by defeating Alberto Berasategui 6–1, 6–3 in the final.

Seeds
• # 🇪🇸 Àlex Corretja (quarterfinals)

• # 🇪🇸 Albert Costa (semifinals, retired)

• # 🇧🇷 Fernando Meligeni (first round)

• # 🇲🇦 Younes El Aynaoui (second round)

• # 🇦🇷 Mariano Zabaleta (first round)

• # 🇪🇸 Fernando Vicente (second round)

• # 🇦🇷 Franco Squillari (first round, retired)

• # 🇪🇸 Juan Carlos Ferrero (second round)