1999 NCAA Division I women's lacrosse tournament

The 1999 NCAA Division I Women's Lacrosse Championship was the 18th annual single-elimination tournament to determine the national champion of Division I NCAA women's college lacrosse. The championship game was played at Homewood Field in Baltimore, Maryland during May 1999. All NCAA Division I women's lacrosse programs were eligible for this championship. Ultimately, 12 teams were invited to the tournament.

Maryland defeated Virginia, 16–6, to win their seventh and fifth consecutive, national championship. This was a rematch of the previous year's final, also won by the Terrapins. This would subsequently become the fifth of Maryland's record seven straight national titles (1995–2001). Furthermore, Maryland's win secured an undefeated season (21–0) for the team.

The leading scorer for the tournament, with 16 goals, was Jen Adams from Maryland. Adams was also named the tournament's Most Outstanding Player.

Tournament outstanding players

 * Sandy Johnston, Duke
 * Kate Kaiser, Duke
 * Jen Adams, Maryland (Most outstanding player)
 * Allison Comito, Maryland
 * Christie Jenkins, Maryland
 * Alex Kahoe, Maryland
 * Kristin Sommar, Maryland
 * Colleen O'Brien, Penn State
 * Jen Webb, Penn State
 * Kelly Allenbach, Virginia
 * Melissa Hayes, Virginia
 * Gina Sambus, Virginia