1999 Tashkent Open – Singles

The 1999 Tashkent Open singles was the singles event of the first edition of the Tashkent Open; a WTA Tier IVb tournament and the most prestigious women's tennis tournament held in Central Asia.

Anna Smashnova won in the final 6–3, 6–3 against Laurence Courtois, to win what was her first WTA Tour title.

Seeds
• # 🇮🇱 Anna Smashnova (champion)

• # 🇷🇺 Tatiana Panova (second round)

• # 🇧🇪 Laurence Courtois (final)

• # 🇷🇺 Evgenia Kulikovskaya (first round)

• # 🇮🇹 Adriana Serra Zanetti (second round)

• # 🇦🇹 Patricia Wartusch (second round)

• # Seda Noorlander (first round)

• # 🇺🇸 Meilen Tu (first round)

Seeds
• # n.a.

• # 🇯🇵 Haruka Inoue (first round)

• # 🇮🇱 Nataly Cahana (qualifying competition)

• # 🇧🇾 Nadejda Ostrovskaya (qualifying competition)

• # 🇩🇪 Adriana Barna (first round)

• # 🇷🇺 Anastasia Myskina (Qualifier)

• # 🇯🇵 Keiko Nagatomi (Qualifier)

• # 🇩🇪 Angelika Bachmann (Qualifier)

• # 🇷🇺 Maria Goloviznina (first round)

Qualifiers
• # 🇩🇪 Angelika Bachmann

• # 🇷🇺 Anastasia Myskina

• # 🇺🇦 Anna Zaporozhanova

• # 🇯🇵 Keiko Nagatomi