1999 US Open – Women's doubles

Serena and Venus Williams defeated Chanda Rubin and Sandrine Testud in the final, 4–6, 6–1, 6–4 to win the women's doubles tennis title at the 1999 US Open. It was the second doubles major title for the Williams sisters, and their second step towards completing the career Golden Slam in doubles.

Martina Hingis and Jana Novotná were the defending champions, but Hingis did not compete this year. Novotná teamed up with Natasha Zvereva, but they lost in the third round to Liezel Horn and Kimberly Po.

Seeds
• # 🇨🇿 Jana Novotná / 🇧🇾 Natasha Zvereva (third round)

• # 🇫🇷 Alexandra Fusai / 🇫🇷 Nathalie Tauziat (third round)

• # 🇺🇸 Lindsay Davenport / 🇺🇸 Corina Morariu (quarterfinals)

• # 🇷🇺 Elena Likhovtseva / 🇯🇵 Ai Sugiyama (first round)

• # 🇺🇸 Serena Williams / 🇺🇸 Venus Williams (champions)

• # Larisa Neiland / 🇪🇸 Arantxa Sánchez Vicario (semifinals)

• # 🇺🇸 Lisa Raymond / 🇦🇺 Rennae Stubbs (third round)

• # Mariaan de Swardt / 🇺🇦 Elena Tatarkova (first round)

• # 🇷🇴 Irina Spîrlea / Caroline Vis (first round)

• # 🇺🇸 Mary Joe Fernández / 🇺🇸 Monica Seles (quarterfinals)

• # 🇪🇸 Conchita Martínez / 🇦🇷 Patricia Tarabini (third round)

• # 🇫🇷 Mary Pierce / 🇦🇹 Barbara Schett (semifinals)

• # 🇪🇸 Virginia Ruano Pascual / 🇦🇷 Paola Suárez (second round)

• # Cara Black / 🇰🇿 Irina Selyutina (first round)

• # 🇺🇸 Nicole Arendt / Manon Bollegraf (quarterfinals)

• # Liezel Horn / 🇺🇸 Kimberly Po (quarterfinals)