2-Bromobutyric acid

2-Bromobutyric acid is the organic compound with the molecular formula CH3CH2CH(Br)CO2H. It is a colorless liquid.

The 2-position is stereogenic, so the compound is chiral. Optical resolution can be effected using strychnine.

2-Bromobutyric acid is used as a building block chemical, such as in the preparation of Levetiracetam, an anticonvulsant medication.

Production
(±)-2-Bromobuyric acid may be prepared by the acid-catalyzed Hell–Volhard–Zelinsky reaction, where butyric acid is treated with elemental bromine. It is one of many compounds that arise adventiously from the use of bromine as an antiseptic.


 * Synthesis 2-Bromobutyric acid A.svg