2000–01 Primera División A season

Primera División A (Méxican First A Division) is a Mexican football tournament. This season was composed of Invieno 2000 and Verano 2001. Reboceros de La Piedad was the winner of the promotion to First Division after winning Gallos de Aguascalientes in the promotion playoff.

Changes for the 2000–01 season

 * The Jaguares de Colima spot in Primera 'A' was bought by Halcones de Querétaro, Halcones remained in the league, Jaguares had dissolved.
 * Toros Neza was relegated from Primera Division.
 * Potros Marte was promoted from Second Division.

Changes for Verano 2001

 * Ángeles de Puebla was acquired by the Universidad Cuauhtémoc and its name was changed to Real San Sebastián.

Promotion final
The Promotion Final faced Gallos de Aguascalientes against Reboceros de La Piedad to determine the winner of the First Division Promotion.

First division promotion playoff
The Mexican Football Federation decided to increase the number of teams in the Primera División to 19 participants, so it was decided to play a promotion series between Atlante, the last place in the Primera División relegation table, and Veracruz, which was the team with most points in the Primera A season. Finally, Atlante was the winner and remained in Primera División.

Relegation playoff
A relegation series faced Halcones de Querétaro, last team in the Primera A relegation table, against Potros Zitácuaro, champion of the Second Division.