2000 Acura Classic – Singles

Serena Williams was the defending champion, but did not compete this year.

Venus Williams won the title by defeating Monica Seles 6–0, 6–7(3–7), 6–3 in the final. It was the 3rd title for Williams in the season and the 12th title in her career.

Seeds
The first four seeds received a bye into the second round. • # Martina Hingis (quarterfinals)

• # 🇺🇸 Lindsay Davenport (second round)

• # 🇺🇸 Venus Williams (champion)

• # 🇺🇸 Monica Seles (final)

• # 🇪🇸 Conchita Martínez (quarterfinals)

• # 🇫🇷 Nathalie Tauziat (quarterfinals)

• # 🇩🇪 Anke Huber (first round)

• # 🇫🇷 Sandrine Testud (quarterfinals)