2000 Cal State Northridge Matadors football team

The 2000 Cal State Northridge Matadors football team represented California State University, Northridge as a member of the Big Sky Conference during the 2000 NCAA Division I-AA football season. Led by second-year head coach Jeff Kearin, Cal State Northridge compiled an overall record of 4–7 with a mark of 2–6 in conference play, tying for seventh place in the Big Sky. The Matadors played home games at North Campus Stadium in Northridge, California.