2000 Franklin Templeton Tennis Classic – Singles

Jan-Michael Gambill was the defending champion, but did not participate this year.

Lleyton Hewitt won the title, defeating Tim Henman 6–4, 7–6(7–2) in the final.

Seeds

 * 1) 🇺🇸 Andre Agassi (second round)
 * 2) 🇺🇸 Pete Sampras (second round, withdrew)
 * 3)  Marcelo Ríos (quarterfinals, retired)
 * 4) 🇪🇨 Nicolás Lapentti (quarterfinals)
 * 5) 🇬🇧 Tim Henman (final)
 * 6) 🇦🇺 Lleyton Hewitt (champion)
 * 7) 🇪🇸 Álbert Costa (semifinals)
 * 8) 🇦🇺 Patrick Rafter (first round)