2000 Indian Wells Masters – Women's singles

Lindsay Davenport defeated Martina Hingis in the final, 4–6, 6–4, 6–0 to win the women's singles tennis title at the 2000 Indian Wells Masters.

Serena Williams was the defending champion, but lost in the quarterfinals to Mary Pierce in a rematch of the last year's quarterfinal.

Seeds
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.

• # Martina Hingis (final)

• # 🇺🇸 Lindsay Davenport (champion)

• # 🇺🇸 Serena Williams (quarterfinals)

• # 🇫🇷 Nathalie Tauziat (second round)

• # 🇫🇷 Mary Pierce (semifinals)

• # 🇪🇸 Conchita Martínez (quarterfinals)

• # 🇺🇸 Monica Seles (quarterfinals)

• # 🇷🇺 Anna Kournikova (second round)

• # 🇫🇷 Julie Halard-Decugis (third round)

• # 🇦🇹 Barbara Schett (third round)

• # 🇫🇷 Sandrine Testud (second round)

• # 🇺🇸 Jennifer Capriati (first round)

• # 🇫🇷 Amélie Mauresmo (first round, retired)

• # 🇩🇪 Anke Huber (first round)

• # Amanda Coetzer (first round)

• # 🇷🇺 Elena Likhovtseva (third round)

Qualifying seeds
• # 🇭🇺 Rita Kuti-Kis (qualifying competition, Lucky loser)

• # Kristie Boogert (first round)

• # Tina Pisnik (qualified)

• # 🇨🇦 Sonya Jeyaseelan (qualified)

• # 🇺🇸 Meghann Shaughnessy (qualifying competition, Lucky loser)

• # 🇩🇪 Marlene Weingärtner (qualified)

• # Mariaan de Swardt (first round)

• # 🇧🇪 Els Callens (first round)

Qualifiers
• # 🇨🇦 Jana Nejedly

• # Janet Lee

• # 🇨🇦 Sonya Jeyaseelan

• # 🇺🇸 Brie Rippner

• # 🇩🇪 Marlene Weingärtner

• # Tina Pisnik

• # 🇺🇸 Marissa Irvin

• # 🇷🇺 Alina Jidkova

Lucky losers
• # 🇭🇺 Rita Kuti-Kis

• # 🇺🇸 Meghann Shaughnessy