2000 Kremlin Cup – Men's singles

Yevgeny Kafelnikov was the defending champion and won in the final 6–2, 7–5 against David Prinosil.

Seeds
• # 🇷🇺 Marat Safin (semifinals)

• # 🇷🇺 Yevgeny Kafelnikov (champion)

• # Sjeng Schalken (withdrew)

• # Marc Rosset (semifinals)

• # 🇫🇷 Fabrice Santoro (first round)

• # 🇧🇾 Max Mirnyi (second round)

• # 🇪🇸 Fernando Vicente (first round)

• # 🇨🇿 Jiří Novák (second round)

Qualifying seeds
• # 🇨🇿 Bohdan Ulihrach (first round)

• # 🇦🇲 Sargis Sargsian (first round)

• # 🇨🇿 Michal Tabara (first round)

• # Jan Siemerink (first round)

• # Goran Ivanišević (qualified)

• # 🇫🇮 Tuomas Ketola (qualifying competition, lucky loser)

• # Kevin Ullyett (second round)

• # 🇸🇰 Ján Krošlák (qualified)

Qualifiers
• # Kristian Pless

• # 🇸🇰 Ján Krošlák

• # 🇩🇪 Lars Burgsmüller

• # Goran Ivanišević

Lucky losers
• # 🇫🇮 Tuomas Ketola

• # 🇩🇪 Björn Phau

• # 🇨🇦 Daniel Nestor