2000 Liga de Fútbol Profesional Boliviano

The 2000 season of the Liga de Fútbol Profesional Boliviano was the 43rd season of top-tier football in Bolivia.

Promotion/relegation
Real Santa Cruz remain at 1st level; Iberoamericano (farm team of Bolívar) won promotion

Copa Libertadores
The Strongest won on points total and qualified for the Copa Libertadores 2001

Championship
Jorge Wilstermann won 3-4 on penalties, with keeper Mauricio Soria saving four penalty kicks, and qualified for the Copa Libertadores 2001