2000 Open Gaz de France – Singles

Serena Williams was the defending champion, but lost in the final 7–5, 6–2 against Nathalie Tauziat.

Seeds
The top four seeds received a bye to the second round. • # 🇺🇸 Serena Williams (final)

• # 🇫🇷 Nathalie Tauziat (champion)

• # 🇫🇷 Julie Halard-Decugis (semifinals)

• # 🇷🇺 Anna Kournikova (semifinals)

• # 🇫🇷 Amélie Mauresmo (second round)

• # 🇫🇷 Sandrine Testud (first round)

• # 🇷🇺 Elena Likhovtseva (first round)

• # 🇧🇪 Dominique Van Roost (first round)