2000 St. Petersburg Open – Singles

Marc Rosset was the defending champion but lost in the first round 6–1, 3–6, 3–6 against Andrei Stoliarov.

Marat Safin won in the final 2–6, 6–4, 6–4 against Dominik Hrbatý.

Seeds
• # 🇷🇺 Marat Safin (champion)

• # 🇷🇺 Yevgeny Kafelnikov (semifinals)

• # 🇸🇰 Dominik Hrbatý (final)

• # Marc Rosset (first round)

• # Sjeng Schalken (second round)

• # 🇧🇾 Max Mirnyi (first round)

• # 🇩🇪 David Prinosil (second round)

• # 🇪🇸 Fernando Vicente (first round)