2001 Abierto Mexicano Pegaso – Men's singles

Juan Ignacio Chela was the defending champion but did not compete that year.

Gustavo Kuerten won in the final 6–4, 6–2 against Galo Blanco.

Seeds

 * 1) 🇧🇷 Gustavo Kuerten (champion)
 * 2) 🇦🇷 Franco Squillari (first round)
 * 3) 🇪🇸 Carlos Moyá (semifinals)
 * 4) 🇦🇷 Gastón Gaudio (quarterfinals)
 * 5) 🇪🇸 Albert Costa (second round)
 * 6) 🇪🇸 Fernando Vicente (first round)
 * 7) 🇪🇸 Francisco Clavet (first round)
 * 8) 🇲🇦 Hicham Arazi (second round)

Qualifying seeds
• # 🇪🇸 Tommy Robredo (first round)

• # 🇧🇷 Alexandre Simoni (qualifying competition, lucky loser)

• # 🇦🇹 Markus Hipfl (qualifying competition)

• # Juan Antonio Marín (qualifying competition)

• # 🇪🇸 Óscar Serrano (first round)

• # 🇵🇪 Luis Horna (qualified)

• # 🇳🇴 Christian Ruud (qualified)

• # 🇦🇷 Martín Rodríguez (qualified)

Qualifiers
• # 🇦🇷 Guillermo Cañas

• # 🇵🇪 Luis Horna

• # 🇦🇷 Martín Rodríguez

• # 🇳🇴 Christian Ruud

Lucky loser

 * 1) 🇧🇷 Alexandre Simoni