2001 Brasil Open – Men's singles

Jan Vacek won in the final 2–6, 7–6(7–2), 6–3 against Fernando Meligeni.

Seeds

 * 1) 🇧🇷 Gustavo Kuerten (first round)
 * 2) 🇦🇷 Guillermo Cañas (quarterfinals)
 * 3) 🇧🇾 Vladimir Voltchkov (first round)
 * 4)  Nicolás Massú (second round)
 * 5) 🇧🇷 Fernando Meligeni (final)
 * 6) 🇧🇷 Alexandre Simoni (semifinals)
 * 7) 🇦🇷 Agustín Calleri (semifinals)
 * 8) 🇦🇷 Mariano Zabaleta (second round)