2001 Ericsson Open – Men's singles

Andre Agassi defeated Jan-Michael Gambill in the final, 7–6(7–4), 6–1, 6–0 to win the men's singles tennis title at the 2001 Miami Open. With the win, he completed the Sunshine Double.

Pete Sampras was the defending champion, but lost in the third round to wildcard Andy Roddick.

Seeds
All thirty-two seeds received a bye to the second round. • # 🇧🇷 Gustavo Kuerten (third round)

• # 🇷🇺 Marat Safin (second round)

• # 🇺🇸 Andre Agassi (champion)

• # 🇺🇸 Pete Sampras (third round)

• # 🇷🇺 Yevgeny Kafelnikov (third round)

• # 🇸🇪 Magnus Norman (third round)

• # 🇦🇺 Lleyton Hewitt (semifinals)

• # 🇦🇺 Patrick Rafter (semifinals)

• # 🇬🇧 Tim Henman (second round)

• # 🇪🇸 Àlex Corretja (fourth round)

• # 🇫🇷 Arnaud Clément (third round)

• # 🇪🇸 Juan Carlos Ferrero (fourth round)

• # 🇸🇰 Dominik Hrbatý (third round)

• # 🇸🇪 Thomas Enqvist (third round)

• # 🇫🇷 Sébastien Grosjean (third round)

• # 🇦🇺 Mark Philippoussis (third round)

• # Wayne Ferreira (second round)

• # 🇦🇷 Franco Squillari (second round)

• # 🇺🇸 Jan-Michael Gambill (final)

• # 🇫🇷 Cédric Pioline (second round)

• # Andrei Pavel (fourth round)

• # 🇪🇸 Carlos Moyá (fourth round)

• # 🇩🇪 Tommy Haas (fourth round, withdrew because of a foot injury)

• # Roger Federer (quarterfinals)

• # 🇸🇪 Thomas Johansson (fourth round)

• # Marcelo Ríos (second round)

• # 🇧🇾 Vladimir Voltchkov (second round)

• # 🇪🇨 Nicolás Lapentti (third round)

• # 🇪🇸 Francisco Clavet (third round)

• # 🇩🇪 David Prinosil (third round)

• # 🇦🇷 Gastón Gaudio (quarterfinals)

• # 🇫🇷 Nicolas Escudé (second round)