2001 Estoril Open – Men's singles

This tournament took place between April 9 and 15, 2001.

Carlos Moyá was the defending champion but did not compete that year.

Juan Carlos Ferrero won in the final 7–6(7–3), 4–6, 6–3 against Félix Mantilla.

Seeds
• # 🇪🇸 Juan Carlos Ferrero (champion)

• # 🇬🇧 Tim Henman (second round)

• # 🇸🇰 Dominik Hrbatý (quarterfinals)

• # 🇦🇷 Franco Squillari (quarterfinals)

• # Andrei Pavel (semifinals)

• # 🇺🇸 Michael Chang (first round)

• # 🇪🇨 Nicolás Lapentti (first round)

• # 🇪🇸 Albert Costa (first round)