2001 Heineken Trophy – Men's singles

Patrick Rafter was the defending champion but lost in the first round to Peter Wessels.

Lleyton Hewitt won in the final 6–3, 6–4 against Guillermo Cañas.

Seeds
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.


 * 1) 🇦🇺 Lleyton Hewitt (champion)
 * 2) 🇦🇺 Patrick Rafter (first round)
 * 3) 🇫🇷 Arnaud Clément (first round)
 * 4)  Roger Federer (semifinals)
 * 5) 🇸🇰 Dominik Hrbatý (first round)
 * 6) 🇲🇦 Hicham Arazi (second round)
 * 7)  Sjeng Schalken (quarterfinals)
 * 8) 🇧🇾 Vladimir Voltchkov (first round)