2001 Salem Open – Singles

Nicolas Kiefer was the defending champion but did not compete that year.

Marcelo Ríos won in the final 7–6 (7–3), 6–2 against Rainer Schüttler.

Seeds
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.


 * 1) 🇪🇸 Juan Carlos Ferrero (quarterfinals)
 * 2) 🇷🇺 Marat Safin (second round)
 * 3) 🇫🇷 Sébastien Grosjean (quarterfinals)
 * 4) 🇺🇸 Andy Roddick (first round)
 * 5) 🇦🇺 Mark Philippoussis (second round)
 * 6) 🇸🇪 Jonas Björkman (quarterfinals)
 * 7) 🇺🇸 Michael Chang (second round)
 * 8)  Marcelo Ríos (champion)