2001 TennisCup Vlaanderen – Singles

Amanda Coetzer was the defending champion, but did not compete this year.

Barbara Rittner won the title by defeating Klára Koukalová 6–3, 6–2 in the final.

Seeds
• # 🇹🇭 Tamarine Tanasugarn (first round)

• # 🇺🇸 Jennifer Hopkins (first round)

• # 🇪🇸 Cristina Torrens Valero (first round)

• # 🇮🇱 Anna Smashnova (quarterfinals)

• # 🇩🇪 Barbara Rittner (champion)

• # 🇺🇿 Iroda Tulyaganova (first round)

• # 🇳🇿 Pavlina Nola (first round)

• # 🇪🇸 Virginia Ruano Pascual (quarterfinals)