2003 French Open – Women's singles

Justine Henin-Hardenne defeated Kim Clijsters in the final, 6–0, 6–4 to win the women's singles tennis title at the 2003 French Open. It was her first major singles title, and she became the first Belgian to win a major; Clijsters (also Belgian) was attempting to achieve the same accolade. The final made Belgium the third country in the Open Era (following Australia and the United States) to have two countrywomen contest a major final.

Serena Williams was the defending champion, but was defeated by Henin-Hardenne in the semifinals, ending her winning streak of 33 major matches.

This marked the final major appearance of former world No. 1 and nine-time major champion Monica Seles, who was defeated by Nadia Petrova in the first round. This was Seles' only first-round loss at a major in her career. It was also the first French Open appearance for future world No. 1 and five-time major champion Maria Sharapova, who was defeated by Magüi Serna in the first round.

Seeds
• # 🇺🇸 Serena Williams (semifinals)

• # 🇧🇪 Kim Clijsters (final)

• # 🇺🇸 Venus Williams (fourth round)

• # 🇧🇪 Justine Henin-Hardenne (champion)

• # 🇫🇷 Amélie Mauresmo (quarterfinals)

• # 🇺🇸 Lindsay Davenport (fourth round)

• # 🇺🇸 Jennifer Capriati (fourth round)

• # 🇺🇸 Chanda Rubin (quarterfinals)

• # 🇸🇰 Daniela Hantuchová (second round)

• # Jelena Dokić (second round)

• # 🇷🇺 Anastasia Myskina (second round)

• # 🇺🇸 Monica Seles (first round)

• # 🇷🇺 Elena Dementieva (first round)

• # Eleni Daniilidou (third round)

• # 🇧🇬 Magdalena Maleeva (fourth round)

• # 🇯🇵 Ai Sugiyama (fourth round)

• # Amanda Coetzer (first round)

• # 🇺🇸 Meghann Shaughnessy (third round)

• # Patty Schnyder (fourth round)

• # 🇷🇺 Elena Bovina (second round)

• # 🇺🇸 Lisa Raymond (second round)

• # 🇷🇺 Vera Zvonareva (quarterfinals)

• # 🇮🇱 Anna Pistolesi (second round)

• # 🇪🇸 Conchita Martínez (quarterfinals)

• # 🇫🇷 Nathalie Dechy (third round)

• # 🇮🇹 Silvia Farina Elia (third round)

• # 🇺🇸 Alexandra Stevenson (first round)

• # 🇦🇷 Clarisa Fernández (second round)

• # 🇷🇺 Elena Likhovtseva (first round)

• # 🇦🇷 Paola Suárez (third round)

• # 🇺🇸 Laura Granville (third round)

• # 🇮🇹 Francesca Schiavone (second round)