2003 Prairie View A&M Panthers football team

The 2003 Prairie View A&M Panthers football team represented Prairie View A&M University as a member of the Southwestern Athletic Conference (SWAC) during the 2003 NCAA Division I-AA football season. Led by first-year head coach C. L. Whittington, the Panthers compiled an overall record of 1–10, with a mark of 0–7 in conference play, and finished fifth in the SWAC West Division.