2003 U.S. Men's Clay Court Championships – Singles

Andy Roddick was the defending champion but lost in the final 3–6, 6–3, 6–4 against Andre Agassi.

Seeds
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.


 * 1) 🇺🇸 Andre Agassi (champion)
 * 2) 🇺🇸 Andy Roddick (final)
 * 3) 🇺🇸 James Blake (quarterfinals)
 * 4) 🇺🇸 Taylor Dent (first round)
 * 5) 🇺🇸 Vince Spadea (second round)
 * 6) 🇺🇸 Jan-Michael Gambill (first round)
 * 7) 🇺🇸 Robby Ginepri (withdrew because of a right hand injury)
 * 8) 🇰🇷 Hyung-Taik Lee (first round)