2004–05 Northern Iowa Panthers men's basketball team

The 2004–05 Northern Iowa Panthers men's basketball team represented the University of Northern Iowa during the 2004–05 NCAA Division I men's basketball season. The Panthers, led by fourth-year head coach Greg McDermott, played their home games at the UNI-Dome in Cedar Falls, Iowa and were members of the Missouri Valley Conference (The Valley). They finished the season 21–11, 11–7 in MVC play to finish in third place. They lost to SW Missouri State in the Missouri Valley tournament, but still received an at-large bid to the NCAA tournament where they were defeated by No. 6 seed Wisconsin in the opening round.

Schedule and results
!colspan=9 style=| Non-Conference Regular season

!colspan=9 style=| Missouri Valley Conference Regular season

!colspan=9 style=| Missouri Valley tournament

!colspan=9 style=| NCAA tournament