2004 Acura Classic – Singles

Lindsay Davenport defeated Anastasia Myskina in the final, 6–1, 6–1 to win the singles tennis title at the 2004 Southern California Open.

Justine Henin was the reigning champion, but withdrew due to a virus.

Seeds
The first eight seeds received a bye into the second round. • # 🇺🇸 Serena Williams (quarterfinals, withdrew due to a left knee inflammation)

• # 🇫🇷 Amélie Mauresmo (second round)

• # 🇷🇺 Anastasia Myskina (final)

• # 🇺🇸 Lindsay Davenport (champion)

• # 🇷🇺 Elena Dementieva (semifinals)

• # 🇷🇺 Maria Sharapova (quarterfinals)

• # 🇷🇺 Svetlana Kuznetsova (third round)

• # 🇯🇵 Ai Sugiyama (quarterfinals)

• # 🇦🇷 Paola Suárez (second round)

• # 🇷🇺 Nadia Petrova (first round)

• # 🇺🇸 Venus Williams (withdrew due to a right wrist sprain)

• # 🇷🇺 Vera Zvonareva (semifinals)

• # Patty Schnyder (first round)

• # 🇮🇱 Anna Smashnova-Pistolesi (first round)

• # 🇮🇹 Francesca Schiavone (first round)

• # 🇮🇹 Silvia Farina Elia (first round)