2004 Prairie View A&M Panthers football team

The 2004 Prairie View A&M Panthers football team represented Prairie View A&M University as a member of the Southwestern Athletic Conference (SWAC) during the 2004 NCAA Division I-AA football season. Led by first-year head coach Henry Frazier III, the Panthers compiled an overall record of 3–8, with a mark of 1–6 in conference play, and finished fourth in the SWAC West Division.