2005–06 Creighton Bluejays men's basketball team

The 2005–06 Creighton Bluejays men's basketball team represented Creighton University in the 2005–06 NCAA Division I men's basketball season. Led by head coach Dana Altman in his 12th season, the Bluejays would end the season with a record of 20–10 (12-6 MVC). They qualified for the NIT where they defeated Akron before losing to Miami (FL) in the second round.

Schedule and results
!colspan=9 style=| Exhibition

!colspan=9 style=| Regular season

!colspan=9 style=| Missouri Valley Tournament

!colspan=9 style=| NIT

Postseason
2006 Missouri Valley Conference men's basketball tournament 3/3/06 Vs. Bradley @ Savvis Center L, 47-54 2006 National Invitation Tournament 3/16/06 Vs. Akron @ Qwest Center Omaha W, 71-60 3/20/06 Vs. Miami (FL) @ Qwest Center Omaha L, 52-53