2005–06 Eerste Klasse

2005–06 Eerste Klasse was a Dutch association football season of the Eerste Klasse.

Saturday champions were:
 * A: SV Huizen
 * B: TOGR
 * C: SSV '65
 * D: VV Nunspeet
 * E: Oranje Nassau Groningen

Sunday champions were:
 * A: HVV Hollandia
 * B: VUC Den Haag
 * C: Blauw Geel '38
 * D: RKSV Groene Ster
 * E: SC Enschede
 * F: Meppeler Sport Club