2005–06 LSU Lady Tigers basketball team

The 2005–06 LSU Lady Tigers basketball team represented Louisiana State University during the 2005–06 NCAA Division I women's basketball season college basketball season. The Lady Tigers, were led by second-year head coach Pokey Chatman, played their home games at Pete Maravich Assembly Center, and were members of the Southeastern Conference. They finished the season 31–4, 13–1 in SEC play to finish atop the conference regular season standings. As the one seed in the SEC women's tournament, they lost in the championship game to Tennessee. They received an at-large bid to the NCAA women's tournament as the No. 1 seed in the San Antonio (SAN) region. The Lady Tigers defeated Florida Atlantic, Washington, DePaul, and Stanford to reach the Final Four for the third straight season. LSU was beaten in the National semifinals by Duke.

Schedule and results
!colspan=12 style="background:#33297B; color:#FDD023;"| Regular season

!colspan=12 style="background:#33297B;" | SEC Women's Tournament

!colspan=12 style="background:#33297B;" | NCAA Tournament

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