2005–06 Old Dominion Monarchs basketball team

The 2005–06 Old Dominion Monarchs basketball team represented Old Dominion University in National Collegiate Athletic Association (NCAA) Division I men's basketball during the 2005–06 season. Playing in the Colonial Athletic Association (CAA) and led by fifth-year head coach Blaine Taylor, the Monarchs finished the season with a 24–10 overall record (13–5 CAA).

The Monarchs competed in the 2005 Paradise Jam and lost to Wisconsin in the in-season tournament championship after winning their first two round-robin games. After losing to Northeastern in the CAA tournament quarterfinal, Old Dominion received a qualifying bid to the 2006 National Invitation Tournament. Playing as the No. 5 seed in the Maryland bracket, ODU proceeded to winning out the bracket after defeating Hofstra in the tournament quarterfinal. They lost to Michigan in the tournament semifinal.

Schedule and results
!colspan=9 style=| Exhibition

!colspan=9 style=| Non-conference regular season

!colspan=9 style=| CAA regular season

!colspan=9 style=| CAA tournament

!colspan=9 style=| National Invitation Tournament