2005 Copa Petrobras Santiago – Singles

Óscar Hernández was the defending champion, but lost in semifinals to Rubén Ramírez Hidalgo.

Júlio Silva defeated Rubén Ramírez Hidalgo 6–2, 6–3 in the final.

Seeds
• # 🇪🇸 Fernando Vicente (second round)

• # 🇪🇸 Óscar Hernández (semifinals)

• # 🇦🇷 Carlos Berlocq (withdrew due to a right shoulder injury)

• # 🇧🇷 Flávio Saretta (first round)

• # Boris Pašanski (quarterfinals)

• # 🇦🇹 Oliver Marach (second round)

• # Juan Antonio Marín (quarterfinals)

• # 🇪🇸 Rubén Ramírez Hidalgo (final)