2005 Internationaux de Strasbourg – Singles

Claudine Schaul was the defending champion, but lost in the first round to Amy Frazier.

Anabel Medina Garrigues won the title, defeating Marta Domachowska in the final 6–4, 6–3.

Seeds
• # 🇫🇷 Nathalie Dechy (semifinals)

• # 🇫🇷 Tatiana Golovin (second round)

• # 🇮🇹 Silvia Farina Elia (first round)

• # 🇯🇵 Shinobu Asagoe (first round)

• # 🇯🇵 Ai Sugiyama (second round)

• # Karolina Šprem (quarterfinals)

• # 🇺🇸 Amy Frazier (second round)

• # 🇦🇷 Paola Suárez (second round)