2005 JPMorgan Chase Open – Singles

Lindsay Davenport was the defending champion, but withdrew due to a lower-back strain.

Kim Clijsters won the title, defeating Daniela Hantuchová 6–4, 6–1 in the final.

Seeds
The top eight seeds receive a bye into the second round. • # 🇷🇺 Maria Sharapova (quarterfinals, withdrew due to a strained chest muscle)

• # 🇷🇺 Svetlana Kuznetsova (second round)

• # 🇷🇺 Elena Dementieva (semifinals)

• # 🇷🇺 Nadia Petrova (quarterfinals)

• # 🇧🇪 Kim Clijsters (champion)

• # 🇫🇷 Mary Pierce (withdrew due to a right thigh strain)

• # 🇷🇺 Vera Zvonareva (withdrew due to a left ankle sprain)

• # 🇷🇺 Elena Likhovtseva (withdrew due to a gastro intestinal illness)

• # 🇸🇰 Daniela Hantuchová (final)

• # 🇮🇹 Flavia Pennetta (first round)

• # 🇯🇵 Shinobu Asagoe (first round)

• # 🇷🇺 Dinara Safina (third round)

• # 🇮🇹 Francesca Schiavone (semifinals)

• # 🇦🇷 Gisela Dulko (second round)

• # 🇨🇿 Klára Koukalová (third round)

• # 🇷🇺 Anna Chakvetadze (third round)

• # 🇫🇷 Marion Bartoli (third round)