2005 Medibank International – Men's singles

Lleyton Hewitt was the defending champion.

Hewitt successfully defended his title, defeating Ivo Minář 7–5, 6–0 in the final.

Seeds
• # 🇦🇺 Lleyton Hewitt (champion)

• # 🇪🇸 Carlos Moyá (first round)

• # 🇸🇪 Joachim Johansson (second round, retired because of a right hamstring injury)

• # 🇷🇴 Andrei Pavel (quarterfinals)

• # 🇪🇸 Feliciano López (quarterfinals)

• # 🇷🇺 Nikolay Davydenko (first round)

• # 🇸🇪 Thomas Johansson (quarterfinals)

• # 🇺🇸 Taylor Dent (quarterfinals, retired because of viral gastroenteritis)