2006 AIG Japan Open Tennis Championships – Women's singles

Nicole Vaidišová was the defending champion, but did not compete this year.

First-seeded Marion Bartoli won the title by defeating Aiko Nakamura 2–6, 6–2, 6–2 in the final.

Seeds
• # 🇫🇷 Marion Bartoli (champion)

• # 🇯🇵 Ai Sugiyama (quarterfinals)

• # 🇷🇺 Maria Kirilenko (first round)

• # 🇪🇸 Anabel Medina Garrigues (second round, retired due to a left hamstring strain)

• # 🇸🇪 Sofia Arvidsson (first round)

• # 🇦🇷 Gisela Dulko (first round)

• # 🇨🇿 Lucie Šafářová (first round)

• # 🇺🇸 Meghann Shaughnessy (first round)