2006 Bank of the West Classic – Singles

Kim Clijsters was the defending champion, and successfully defended her title, defeating Patty Schnyder in the final 6–4, 6–2.

Seeds
The top four seeds received a bye into the second round. • # 🇧🇪 Kim Clijsters (champion)

• # Patty Schnyder (finals)

• # 🇨🇿 Nicole Vaidišová (semifinals)

• # 🇩🇪 Anna-Lena Grönefeld (quarterfinals)

• # 🇸🇰 Daniela Hantuchová (first round)

• # 🇯🇵 Ai Sugiyama (second round)

• # 🇮🇱 Shahar Pe'er (second round)

• # Katarina Srebotnik (first round)