2006 Budapest Grand Prix – Singles

Anna Smashnova was the defending champion and successfully defended her title, by defeating Lourdes Domínguez Lino 6–1, 6–3 in the final. This was Smashnova's final WTA singles title before her retirement in 2007.

Seeds
• # 🇨🇴 Catalina Castaño (quarterfinals)

• # Michaëlla Krajicek (semifinals)

• # 🇨🇿 Klára Zakopalová (first round)

• # 🇨🇿 Iveta Benešová (second round)

• # 🇪🇸 Lourdes Domínguez Lino (final)

• # 🇩🇪 Julia Schruff (first round)

• # 🇸🇰 Martina Suchá (second round)

• # 🇮🇱 Anna Smashnova (champion)