2006 Jackson State Tigers football team

The 2006 Jackson State Tigers football team represented Jackson State University as a member of the Southwestern Athletic Conference (SWAC) during the 2006 NCAA Division I FCS football season. Led by first-year head coach Rick Comegy, the Tigers compiled an overall record of 6–5 and a mark of 5–4 in conference play, and finished tied for second in the SWAC East Division.